xR IVD

FDA 510(k) K241868 · Tempus AI, Inc.

Substantially Equivalent

510(k) numberK241868

Submission

Device name
xR IVD
Applicant
Tempus AI, Inc.
Chicago, IL, US
Received
June 27, 2024
Decision date
September 19, 2025
Decision
Substantially Equivalent (SESE)
Type
Traditional 510(k)
Summary
510(k) summary available from FDA

Official FDA 510(k) record

Device classification

Product code
PZM – Next Generation Sequencing Based Tumor Profiling Test
Device class
Class II (moderate risk)
Regulation
21 CFR 866.6080
Specialty
Pathology

A next-generation sequencing based tumor profiling test is a qualitative in vitro diagnostic test intended to detect mutations in a broad panel of targeted genes that are somatically altered in malignant neoplasms from tumor specimens obtained from patients diagnosed with malignant solid neoplasms using targeted next-generation sequencing.

Other 510(k)s with product code PZM

510(k)DeviceApplicantDecision
K260235CellDx-TissuePZM · Traditional Datar Cancer Genetics Private Limited05/12/2026SE
K250003GENESEEQPRIME NGS Tumor Profiling Assay (FFPE) (GS6005)PZM · Traditional Geneseeq Technology, Inc.08/29/2025SE
K210017ACTOnco, ACTOnco IVDPZM · Traditional Act Genomics12/23/2022SE
K202304NYU Langone Genome PACT (Genome Profiling of Actionable Cancer Targets)PZM · Traditional Nyu Langone Medical Center07/14/2021SE
K192063PGDx elio tissue completePZM · Traditional Personal Genome Diagnostics04/24/2020SE
K190661Omics CorePZM · Traditional Nanthealth, Inc.11/09/2019SE

More from Nanthealth, Inc.

510(k)DeviceDecision
K253699Tempus ECG-PHSAT · Traditional 08/21/2026SE
K250119Tempus ECG-Low EFQYE · Traditional 07/15/2025SE
K233549Tempus ECG-AFSBQ · Traditional 06/21/2024SE

Questions and answers

When was xR IVD cleared by the FDA?

xR IVD (K241868) received a 510(k) decision of Substantially Equivalent on September 19, 2025, 449 days after the submission was received.

What is the product code of K241868?

The FDA product code is PZM – Next Generation Sequencing Based Tumor Profiling Test, a Class II (moderate risk) device regulated under 21 CFR 866.6080.