APEX 3D Total Ankle Replacement System

FDA 510(k) K250641 · Paragon 28, Inc.

Substantially Equivalent

510(k) numberK250641

Submission

Device name
APEX 3D Total Ankle Replacement System
Applicant
Paragon 28, Inc.
Englewood, CO, US
Received
March 4, 2025
Decision date
May 1, 2025
Decision
Substantially Equivalent (SESE)
Type
Traditional 510(k)
Summary
510(k) summary available from FDA

Official FDA 510(k) record

Device classification

Product code
HSN – Prosthesis, Ankle, Semi-Constrained, Cemented, Metal/Polymer
Device class
Class II (moderate risk)
Regulation
21 CFR 888.3110
Specialty
Orthopedic
Implant
Yes

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K253159Prophecy Incompass Surgical Planning SystemHSN · Traditional Wright Medical Technology, Inc. (Stryker)06/16/2026SE
K252454Kinos Total Ankle SystemHSN · Special Restor3D09/03/2025SE
K250037Incompass Total Ankle SystemHSN · Traditional Wright Medical Technology, Inc. (Stryker)06/20/2025SE
K240475Hintermann Series H2 Total Ankle SystemHSN · Traditional Vilex, LLC12/02/2024SE
K241999Prophecy Surgical Planning SystemHSN · Traditional Wright Medical Technology, Inc. (Stryker)11/01/2024SE
K242868Kinos Total Ankle SystemHSN · Special Restor3D10/18/2024SE
K241482Kinos Total Ankle SystemHSN · Traditional Restor3D07/22/2024SE
K240259APEX 3D Total Ankle Replacement SystemHSN · Traditional Paragon 28, Inc.06/24/2024SE
K240591restor3d Kinos Axiom Total Ankle SystemHSN · Traditional Restor3D, Inc.04/29/2024SE
K231699QUANTUM® Patient Specific Instrumentation (PSI) SystemHSN · Traditional In2bones Sas04/23/2024SE

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Questions and answers

When was APEX 3D Total Ankle Replacement System cleared by the FDA?

APEX 3D Total Ankle Replacement System (K250641) received a 510(k) decision of Substantially Equivalent on May 1, 2025, 58 days after the submission was received.

What is the product code of K250641?

The FDA product code is HSN – Prosthesis, Ankle, Semi-Constrained, Cemented, Metal/Polymer, a Class II (moderate risk) device regulated under 21 CFR 888.3110.