cvi42 Coronary Plaque Software Application

FDA 510(k) K251027 · Circle Cardiovascular Imaging, Inc.

Substantially Equivalent

510(k) numberK251027

Submission

Device name
cvi42 Coronary Plaque Software Application
Applicant
Circle Cardiovascular Imaging, Inc.
Calgary, CA
Received
April 2, 2025
Decision date
October 27, 2025
Decision
Substantially Equivalent (SESE)
Type
Traditional 510(k)
Summary
510(k) summary available from FDA

Official FDA 510(k) record

Device classification

Product code
QIH – Automated Radiological Image Processing Software
Device class
Class II (moderate risk)
Regulation
21 CFR 892.2050
Specialty
Radiology

To provide automated radiological image processing and analysis tools. Software implementing artificial intelligence including nonadaptive machine learning algorithms trained with clinical and/or artificial data. In these devices, the algorithm training data typically impacts device performance. Adaptive AI algorithms are not within scope of this product code.

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K260525NextMR SpineQIH · Traditional MRI2CT, Inc.09/04/2026SE
K260811Heartvue.ProtonQIH · Traditional Heartvue.ai, Inc.08/26/2026SE
K261595Ceevra Reveal 4QIH · Traditional Ceevra, Inc.08/25/2026SE
K262127DS Core CBCT AnatomyQIH · Traditional Dentsply Sirona08/21/2026SE
K260584BoneMRIQIH · Traditional Mriguidance B.V.08/21/2026SE
K261641Lower Limb AI (LLAI)QIH · Traditional AI Planning Logic, Inc.08/18/2026SE
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More from Lucida Medical, Ltd.

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K250221StrokeSENS ASPECTS Software ApplicationPOK · Traditional 07/01/2025SE
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K241038Cardiac CT Function Software ApplicationQIH · Traditional 06/07/2024SE
K232661Myocardial Strain Software ApplicationLLZ · Traditional 12/07/2023SE
K222593TruPlan Computed Tomography (CT) Imaging SoftwareLLZ · Traditional 01/18/2023SE
K213998cvi42 Auto Imaging Software ApplicationQIH · Traditional 07/28/2022SE
K202212TruPlanLLZ · Traditional 02/19/2021SE
K141480CVI42LLZ · Traditional 08/22/2014SE
K111373CT42 Cardiac Computed Tomography (CT) SoftwareLLZ · Traditional 08/23/2011SE
K082628CMR42 Cardiac MRI Imaging System, 2.1.23LLZ · Traditional 11/20/2008SE

Questions and answers

When was cvi42 Coronary Plaque Software Application cleared by the FDA?

cvi42 Coronary Plaque Software Application (K251027) received a 510(k) decision of Substantially Equivalent on October 27, 2025, 208 days after the submission was received.

What is the product code of K251027?

The FDA product code is QIH – Automated Radiological Image Processing Software, a Class II (moderate risk) device regulated under 21 CFR 892.2050.