Amplatzer™ Amulet™ Left Atrial Appendage Occluder

FDA premarket approval P200049 · System, appendage closure, left atrial

PMA numberP200049

Approval

Applicant
Abbott Medical
Received
December 31, 2020
Decision date
August 14, 2021 (APPR)
Supplements
19, latest August 28, 2026
Product code
NGV – System, Appendage Closure, Left Atrial

Official FDA PMA record

Approval order statement

Approval for The Amplatzer Amulet Left Atrial Appendage Occluder. The device is a percutaneous transcatheter device intended to reduce the risk of thrombus embolization from the left atrial appendage (LAA) in patients who have nonvalvular atrial fibrillation and who are at increased risk for stroke and systemic embolism based on CHADS2 or CHA2DS2-VASc scores, are suitable for short term anticoagulation therapy, and have appropriate rationale to seek a non-pharmacologic alternative to oral anticoagulation, taking into consideration the safety and effectiveness of the device.