Heparin, Vascular Access Flush

FDA product code NZW · Class II (moderate risk) · 21 CFR 880.5200 · General Hospital

Enhance the performance of intravascular catheters, to maintain patency of the vascular catheter when it is not in use.

7510(k) clearances
0PMA approvals
44recalls

Manufacturers

510(k) clearances

510(k)DeviceApplicantDecision
K163591BD PosiFlush Heparin Lock Flush SyringeNZW · Special Becton, Dickinson and Company02/27/2017SE
K133446Heparin Lock / Flush SyringesNZW · Traditional Excelsior Medical Corporation11/14/2014SE
K092938Heparin Lock Flush Solution Usp, Models 504401, 504411, 504505, 505701, 504901, 1710NZW · Traditional App Pharmaceuticals, LLC06/18/2010SE
K092491Medefil's Heparin I.V. Flush Syringe 1 Unit/Ml; 10 Units/Ml; and 100 Units/Ml in Various…NZW · Traditional Medefil, Inc.02/03/2010SE
K090680Heparin Lock Flush Solution, Usp BD Posiflush Heparin Lock Flush SyringeNZW · Special Becton, Dickinson & CO06/10/2009SE
K061497Syrex Heparin Lock Flush Syringe, 1 Unit/Ml & 2 Units/MlNZW · Traditional Excelsior Medical Corp.02/23/2007SE
K023740Syrex Pre-Filled SyringeNZW · Traditional Excelsior Medical Corp.05/13/2003SE

Recalls

RecallProductFirmInitiated
Z-1596-2022 Class IIExcelsior Heparin Sodium, Porcine, Preservative Free 100 U / mL Solution Prefilled…Facility Temperature excursions (from June 2021-August 2021) prior to delivery; exposure to higher… Mckesson Medical-Surgical Inc. Corporate…05/25/2022Open, Classified
Z-1989-2016 Class IIExcelsior Disposable Syringe Heparin Lock Flush, USP syringe (5 mL Fill in 10 mL…Certain lots of Heparin Lock Flush, USP Syringes (5 ml Fill in 10 ml Syringe) failed Anti-Factor IIa assay… Excelsior Medical Corp04/28/2016Terminated
Z-1032-2015 Class IIHEPFLUSH-10 (HEPARIN LOCK FLUSH SOLUTION, USP) 100 USP units per 10 mL (10 USP units per…The lot failed pH specification. Fresenius Kabi USA, LLC12/19/2014Terminated
Z-1149-2014 Class IIIHeparin I.V. Flush Syringe is available is pre-filled polypropylene syringes, 100…The bar code that is printed on the Master Carton label does not correspond to the product code fully… Medefil Incorporated02/19/2014Terminated
Z-1808-2012 Class IIChurchill Medical Systems, Inc. A VYGON COMPANY PICC INSERTION TRAY Prefilled syringes…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1807-2012 Class IIChurchill Medical Systems, Inc. DRESSING CHANGE KIT Prefilled syringes included in the…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1806-2012 Class IIChurchill Medical Systems, Inc. VAD ACCESS TRAY Kit Prefilled syringes included in the…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1805-2012 Class IIChurchill Medical Systems, Inc. VAD ACCESS TRAY Kit Prefilled syringes included in the…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1804-2012 Class IIChurchill Medical Systems, Inc. A VYGON Company PICC INSERTION TRAY Kit Prefilled…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1803-2012 Class IIChurchill Medical Systems, Inc. PORT-A-CATH Tray Kit Prefilled syringes included in the…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1802-2012 Class IIChurchill Medical Systems, Inc. A VYGON Company PICC LINE TRAY Kit Prefilled syringes…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1801-2012 Class IIVygon VY(TM)Flush Heparin Lock Flush Syringes, 100 Units per mL, 5mL in a 10mL Flush…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1800-2012 Class IIVygon VY(TM)Flush Heparin Lock Flush Syringes, 100 Units per mL, 3mL in a 10mL Flush…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1799-2012 Class IIVygon VY(TM)Flush Heparin Lock Flush Syringes, 10 Units per mL, 5mL in a 10mL Flush…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1798-2012 Class IIVygon VY(TM)Flush Heparin Lock Flush Syringes, 10 Units per mL, 3mL in a 10mL Flush…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1797-2012 Class IIVygon VY(TM)Flush Heparin Lock Flush Syringes, 1 Unit per mL, 3mL in a 10mL Flush…Manufacturer issued a voluntary recall on multiple lots of VY(TM)Flush Heparin Lock Flush Syringes therefore… Vygon Corporation05/11/2012Terminated
Z-1707-2012 Heparin Lock Flush Solution 100 Unit/mL, USP 3 ml, 4 ml, 5mL, 6 ml fill in a 10 ml Flush…Some lots of Heparin Lock Flush, USP Syringes (3 mL fill in 10 ml syringe, 4 mL fill in 10 ml syringe, 5 mL… Excelsior Medical Corp05/07/2012Terminated
Z-0601-2011 Medefil Heparin I.V. Flush Syringe 1 units/mL; a polypropylene luer locking syringe…The heparin lock flush solution was manufactured with contaminated Heparin Sodium USP Active Pharmaceutical… Medefil Incorporated11/01/2010Terminated
Z-0600-2011 Medefil Heparin I.V. Flush Syringe 10 units/mL; a polypropylene luer locking syringe…The heparin lock flush solution was manufactured with contaminated Heparin Sodium USP Active Pharmaceutical… Medefil Incorporated11/01/2010Terminated
Z-0599-2011 Medefil Heparin I.V. Flush Syringe 100 units/mL; a polypropylene luer locking syringe…The heparin lock flush solution was manufactured with contaminated Heparin Sodium USP Active Pharmaceutical… Medefil Incorporated11/01/2010Terminated
Z-1825-2012 Class IIHEPARIN LOCK FLUSH SOLUTION, USP, 100 USP Units/mL, 1 mL Multiple Dose Vial, plastic…CGMP Deviations: Incomplete documentation associated with test results. App Pharmaceuticals Llc05/20/2010Terminated
Z-1824-2012 Class IIHEPARIN LOCK FLUSH SOLUTION, USP, 10 USP Units/mL, 1 mL Multiple Dose Vial, plastic…CGMP Deviations: Incomplete documentation associated with test results. App Pharmaceuticals Llc05/20/2010Terminated
Z-1602-2008 Tyco Healthcare Monoject Prefill 100UlmL Heparin Lock Flush Syringe 5mL, with BLUNTIP…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1601-2008 Tyco Healthcare Monoject Prefill100U/mL Heparin Lock Flush Syringe 5mL REF # 8881590125…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1600-2008 Tyco Healthcare Monoject Prefill 100U/mL Heparin Lock Flush Syringe 3rnL REF #…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1599-2008 Tyco Healthcare Monoject Prefill 100U/mL Heparin Lock Flush Syringe 10mL REF #…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1598-2008 Tyco Healthcare Monoject Prefill 10U/mL Heparin Lock Flush Syringe 5mL, with BLUNTIP…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1597-2008 Tyco Healthcare Monoject Prefill 10U/mL Heparin Lock Flush Syringe 2.5mL in 3mL syringe…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1596-2008 Tyco Healthcare Tyco HealthcareMonoject Prefill 10U/mL Heparin Lock Flush Syringe 5mL…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1595-2008 Tyco HealthcareMonoject Prefill 10U/mL Heparin Lock Flush Syringe, 3mL REF # 8881580123…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1594-2008 Tyco Healthcare Monoject Prefill 10U/rnL Heparin Lock Flush Syringe, 10ml, REF #…Scientific Protein Laboratories (SPL), disclosed that two lots of Heparin Sodium, USP Active Pharmaceutical… Covidien LP03/28/2008Terminated
Z-1545-2008 Medefil Heparin I.V. Flush Syringe 1 unit/mL; a polypropylene luer locking syringe…The heparin lock flush solution was manufactured from contaminated Heparin Sodium USP Active Pharmaceutical… Medefil Incorporated03/20/2008Terminated
Z-1544-2008 Medefil Heparin I.V. Flush Syringe 10 units/mL; a polypropylene luer locking syringe…The heparin lock flush solution was manufactured from contaminated Heparin Sodium USP Active Pharmaceutical… Medefil Incorporated03/20/2008Terminated
Z-1543-2008 Medifil Heparin I.V. Flush Syringe 100 units/mL; a polypropylene luer locking syringe…The heparin lock flush solution was manufactured from contaminated Heparin Sodium USP Active Pharmaceutical… Medefil Incorporated03/20/2008Terminated
Z-1393-2008 Baxter HEP-LOCK (Preservative-Free Heparin Lock Flush Solution, USP) 100 units/mL-1 mL…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1392-2008 Baxter HEP-LOCK (Preservative-Free Heparin Lock Flush Solution, USP) 10 units/mL-1 mL…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1391-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP) 100 units/mL-30 mL vial, 25 pack, NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1390-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP) 100 units/mL-10 mL vial, 25 pack, NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1389-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP) 100 units/mL-1 mL vial, 25 pack , NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1388-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP) 100 units/mL-2 mL vial, 25 pack, NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1387-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP), 10 units/mL-30 mL vial; 25 pack, NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1386-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP) 10 u/mL-10 mL vial; 25 pack, NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1385-2008 Baxter HEP-LOCK (Heparin Lock Flush Solution, USP), 10 u/mL-2 mL vial, 25 pack…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated
Z-1384-2008 Baxter HEP LOCK (Heparin Lock Flush Solution, USP) 10 u/mL-1mL vial, 25 Pack, NDC…Due to an increase of adverse events in Baxter single and multi-dose Heparin for injection products, which… Baxter Healthcare Corp.02/28/2008Terminated