Recall Z-1881-2013

Siemens Healthcare Diagnostics, Inc · initiated May 10, 2013

Class II Terminated

Class II – products that might cause a temporary health problem or pose a slight threat of a serious nature

Product

ADVIA Centaur Systems TSH3 Ultra ReadyPack ((REF 06491072 - 100 Tests, REF 06491080 - 500 Tests, REF 04862625 - 2500T). Intended to quantitatively measure human thyroid stimulating hormone (TSH, thyrotropin).

Codes / lots: Per recall strategy.

Reason for recall

A rare variant of TSH, identified in a small cluster of patients, is not detected.

FDA-determined cause: Device Design

Action taken

On May 10, 2013, an Important Safety Information notice was sent to all affected Siemens Healthcare Diagnostic customers in the United States. On May 10, 2013, an Urgent Field Safety Notice was sent to all customers outside of the United States. These notices inform the customer that there is a rare variant of TSH, identified in a small cluster of patients that is not detected by some Siemens assays. This notice informs customers that they should continue to use the affected TSH assays as the observed rate of occurrence during a 30-month time period was 0.6 X 10 -7 and there are strong mitigating factors. These mitigating factors include co-interpretation of TSH results in conjunction with thyroxine and TS, patient history and clinical signs and symptoms. Although Siemens believes a look back is not required as the expected frequency of the variant is extremely rare, these notices state that this decision should be made by the medical director.

Details

Recall number
Z-1881-2013
Initiated
May 10, 2013
Posted by FDA
August 6, 2013
Terminated
May 10, 2016
Product code
JLW – Radioimmunoassay, Thyroid-Stimulating Hormone
Quantity
172913
Distribution
Worldwide Distribution-USA (nationwide) and the countries of Canada, AE, AR, AT, AU, BA, BD, BE, BG, BO, BR, BY, CH, CL, CM, CN, CO, CR, CY, CZ, DE, DK, DO, DZ, EC, EE, EG, ES, FI, FR, GB, GR, GT, HK, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JO, JP, KA, KR, KW, KZ, LB, LK, LT, LV, LY, MA, MK, MT, MX, MY, NI, NL, NO, NP, OM, PA, PE, PH, PK, PL, PT, PY, QA, RO, RU, SA, SE, SG, SK, SV, SY, TH, TM…
Recalling firm
Siemens Healthcare Diagnostics, Inc, East Walpole, MA

Official FDA recall record

Other products in the same recall event

RecallProductInitiated
Z-1882-2013 Class IIDimension TSH Flex Reagent Cartridge (REF RF412). Intended to quantitatively measure…A rare variant of TSH, identified in a small cluster of patients, is not detected. 05/10/2013Terminated
Z-1883-2013 Class IIDimension EXL LOCI Module TSHL Flex Reagent Cartridge (REF RF612). Intended to…A rare variant of TSH, identified in a small cluster of patients, is not detected. 05/10/2013Terminated
Z-1884-2013 Class IIDimension Vista System TSH Flex Reagent Cartridge (REF K6412). Intended to…A rare variant of TSH, identified in a small cluster of patients, is not detected. 05/10/2013Terminated
Z-1885-2013 Class IIIMMULITE Systems Third Generation TSH (REF LKTS1 - 100T, LKTS5 - 500T, L2KTS2 - 200T…A rare variant of TSH, identified in a small cluster of patients, is not detected. 05/10/2013Terminated
Z-1886-2013 Class IIIMMULITE Systems Rapid TSH (REF LKRT1 - 100T, LKRT5 - 500 T, L2KRT2 - 200T, L2KRT6 -…A rare variant of TSH, identified in a small cluster of patients, is not detected. 05/10/2013Terminated