HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer)

FDA 510(k) K253876 · Globus Medical, Inc.

Substantially Equivalent

510(k) numberK253876

Submission

Device name
HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer)
Applicant
Globus Medical, Inc.
Audubon, PA, US
Received
December 4, 2025
Decision date
December 22, 2025
Decision
Substantially Equivalent (SESE)
Type
Special 510(k)
Summary
510(k) summary available from FDA

Official FDA 510(k) record

Device classification

Product code
OVE – Intervertebral Fusion Device With Integrated Fixation, Cervical
Device class
Class II (moderate risk)
Regulation
21 CFR 888.3080
Specialty
Orthopedic
Implant
Yes

Intended to stabilize cervical spinal segment to promote fusion in order to restrict motion and decrease pain using bone graft with or without supplemental fixation.

Other 510(k)s with product code OVE

510(k)DeviceApplicantDecision
K261882Pisces-SC Standalone Cervical Interbody SystemOVE · Traditional Osseus Fusions Systems, LLC08/21/2026SE
K261451ZSAlign Cervical Interbody SystemOVE · Traditional ZSFab, Inc.07/31/2026SE
K262094E3D™-C Interbody SystemOVE · Special Evolution Spine07/22/2026SE
K261279DeltaNEC Interbody SystemOVE · Traditional Nexus Spine06/22/2026SE
K252982CONDUIT™ ZERO-P™ VA Secured Spacer SystemOVE · Traditional Avalign Technologies, Inc.06/18/2026SE
K260036NeckTune™ 3D SA Cervical CageOVE · Traditional Medyssey Co, Ltd.06/15/2026SE
K260660SABER-C SystemOVE · Traditional Elevation Spine04/27/2026SE
K253213SAGI Cervical Cage SystemOVE · Traditional ZheJiang Decans Medical Devices Co., Ltd.04/20/2026SE
K252774Uni-C Cervical Cage SystemOVE · Traditional ZheJiang Decans Medical Devices Co., Ltd.04/15/2026SE
K260038E3D™-C Interbody SystemOVE · Special Evolution Spine02/04/2026SE

More from Evolution Spine

510(k)DeviceDecision
K254043TRIVANCE™ Hip StemLPH · Traditional 08/04/2026SE
K262251ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert)JWH · Special 07/31/2026SE
K253739SCRIPT™ Rods, CREO™ Stabilization System, REVERE® Stabilization System, REVERE® 4.5…NKB · Traditional 05/07/2026SE
K253401SCRIPT™ Implant SystemOVD · Traditional 04/29/2026SE
K261043AUTOBAHN™ Nailing SystemHSB · Special 04/24/2026SE
K252166RIB LINK™ Fixation SystemHRS · Traditional 02/26/2026SE
K250599ExcelsiusGPS™ InstrumentsOLO · Traditional 11/05/2025SE
K251161ANTHEM® Fracture SystemHRS · Traditional 08/18/2025SE
K241525ExcelsiusXR™SBF · Traditional 07/08/2025SE
K243456ONVOY™ Acetabular SystemLPH · Traditional 06/06/2025SE

Questions and answers

When was HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer) cleared by the FDA?

HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer) (K253876) received a 510(k) decision of Substantially Equivalent on December 22, 2025, 18 days after the submission was received.

What is the product code of K253876?

The FDA product code is OVE – Intervertebral Fusion Device With Integrated Fixation, Cervical, a Class II (moderate risk) device regulated under 21 CFR 888.3080.