ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert)

FDA 510(k) K262251 · Globus Medical, Inc.

Substantially Equivalent

510(k) numberK262251

Submission

Device name
ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert)
Applicant
Globus Medical, Inc.
Audubon, PA, US
Received
July 1, 2026
Decision date
July 31, 2026
Decision
Substantially Equivalent (SESE)
Type
Special 510(k)
Summary
510(k) summary available from FDA

Official FDA 510(k) record

Device classification

Product code
JWH – Prosthesis, Knee, Patellofemorotibial, Semi-Constrained, Cemented, Polymer/Metal/Polymer
Device class
Class II (moderate risk)
Regulation
21 CFR 888.3560
Specialty
Orthopedic
Implant
Yes

Other 510(k)s with product code JWH

510(k)DeviceApplicantDecision
K260063GSPE SpacerJWH · Traditional The General Hospital Corporation, d/b/a…09/11/2026SE
K262293EVOLUTION MPX™ Total Knee SystemJWH · Traditional Suzhou Microport Orthorecon Co., Ltd.09/10/2026SE
K262341b-ONE® Mobio™ Total Knee System Revision Cemented Tibial Augments, Stem Extensions and…JWH · Traditional B-One Ortho, Corp.09/08/2026SE
K262130ATTUNE Revision Knee SystemJWH · Traditional Depuy Orthopaedics, Inc.09/04/2026SE
K253961SK Knee SystemJWH · Traditional Just Medical Devices (Tianjin) Co., Ltd.09/01/2026SE
K261563Freedom Total Knee System (E-Poly Tibial Liners)JWH · Traditional Maxx Orthopedics, Inc.08/07/2026SE
K261734Klassic Infection Spacer SystemJWH · Traditional Total Joint Orthopedics, Inc.07/23/2026SE
K261458ATTUNE Total Knee System; ATTUNE Cementless Knee SystemJWH · Traditional DePuy Ireland UC06/25/2026SE
K261032NovoKnee (SteriKnee)JWH · Special NovoSource04/27/2026SE
K253793Materialise TKA Guide SystemJWH · Special Materialise NV01/06/2026SE

More from Materialise NV

510(k)DeviceDecision
K254043TRIVANCE™ Hip StemLPH · Traditional 08/04/2026SE
K253739SCRIPT™ Rods, CREO™ Stabilization System, REVERE® Stabilization System, REVERE® 4.5…NKB · Traditional 05/07/2026SE
K253401SCRIPT™ Implant SystemOVD · Traditional 04/29/2026SE
K261043AUTOBAHN™ Nailing SystemHSB · Special 04/24/2026SE
K252166RIB LINK™ Fixation SystemHRS · Traditional 02/26/2026SE
K253876HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer)OVE · Special 12/22/2025SE
K250599ExcelsiusGPS™ InstrumentsOLO · Traditional 11/05/2025SE
K251161ANTHEM® Fracture SystemHRS · Traditional 08/18/2025SE
K241525ExcelsiusXR™SBF · Traditional 07/08/2025SE
K243456ONVOY™ Acetabular SystemLPH · Traditional 06/06/2025SE

Questions and answers

When was ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert) cleared by the FDA?

ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert) (K262251) received a 510(k) decision of Substantially Equivalent on July 31, 2026, 30 days after the submission was received.

What is the product code of K262251?

The FDA product code is JWH – Prosthesis, Knee, Patellofemorotibial, Semi-Constrained, Cemented, Polymer/Metal/Polymer, a Class II (moderate risk) device regulated under 21 CFR 888.3560.